Cristina Mascaró Selected Research

Histone Demethylases

12/2020	First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia.
1/2015	KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.

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Cristina Mascaró Research Topics

Disease

3	Neoplasms (Cancer) 07/2022 - 01/2015
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2022 - 01/2015
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2020 - 12/2018
2	Inflammation (Inflammations) 01/2020 - 09/2012
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 07/2022
1	Multiple Sclerosis 07/2022
1	Mental Disorders (Mental Disorder) 07/2022
1	Demyelinating Diseases (Demyelinating Disease) 07/2022
1	Encephalomyelitis (Myeloencephalitis) 07/2022
1	Neuroinflammatory Diseases 07/2022
1	Virus Diseases (Viral Diseases) 07/2022
1	Central Nervous System Diseases (CNS Diseases) 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2020
1	Memory Disorders (Memory Loss) 01/2020
1	Leukemia 12/2018
1	Carcinoma (Carcinomatosis) 09/2006

Drug/Important Bio-Agent (IBA)

3	vafidemstatIBA 07/2022 - 01/2020
3	Proteins (Proteins, Gene)FDA Link 07/2022 - 09/2006
3	Lysine (L-Lysine)FDA Link 12/2020 - 01/2015
2	Histone DemethylasesIBA 12/2020 - 01/2015
1	Tranylcypromine (Parnate)FDA LinkGeneric 12/2021
1	AminesIBA 12/2021
1	Oxidoreductases (Dehydrogenase)IBA 12/2021
1	Pargyline (Pargyline Hydrochloride)FDA Link 12/2021
1	Phenelzine (Nardil)FDA Link 12/2021
1	Biomarkers (Surrogate Marker)IBA 12/2018
1	Flavin-Adenine Dinucleotide (FAD)IBA 01/2015
1	AntigensIBA 09/2012
1	CytokinesIBA 09/2012

Therapy/Procedure

1	Oral Administration 07/2022